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One year after watching the Mets stumble and bumble toward the trade deadline, a similar scene is playing out in Queens. On Friday night, that included a third straight loss, including back to back defeats to the Colorado Rockies. A packed house in giveaway Mike Piazza jerseys watched Steven Matz labor through six innings and more offensive failures in a ... Leer Más »

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Here we found that deficiency in the Ca2+ 36 sensor STIM1 caused spontaneous activation of STING and enhanced expression of type I interferons under resting conditions in mice and a patient suffering from combined immunodeficiency. Mechanistically, STIM1 associated with STING to retain it in the ER membrane, and co expression of full length or a STING interacting fragment of STIM1 ... Leer Más »

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